Monday, April 2, 2007

Magnetically Enhanced siRNA Transfection

We have added a new set of products that magnetically drive transfection.

MATra products are designed to enhance the transfection capabilties of our i-Fect and pn-Fect kits.

The technique requires lease or purchase of the Universal Magnetic Plate AND for i-Fect and other siRNA transfection reagents, please also purchase the MATra-siRNA Reagent. For pn-Fect and other Nucleic Acid transfectants, you would buy the MATra-A Regeant.
If your cells are in suspension, you will also need MATra-s-Immobilizer.
Manual for All MATra Products
MATra FAQs

Magnet Assisted Transfection Animation

References:


Publications:
Bertram, J. (2006) MATra - Magnet Assisted Transfection: Combining Nanotechnology and Magnetic Forces to Improve Intracellular Delivery of Nucleic Acids. Current Pharmaceutical Biotechnology 7, 277-285.

Goulimari, P., Kitzing, T.M., Knieling, H., Brandt, D. T., Offermanns, S.
and Grosse, R. (2005) G?12/13 Is Essential for Directed Cell Migration and Localized Rho-Dia1 Function. J. Biol. Chem., Vol. 280, Issue 51, 42242-42251.

Kumbrink, J., Gerlinger, M., and Johnson, J.P. (2005) Egr-1 Induces the Expression of Its Corepressor Nab2 by Activation of the Nab2 Promoter Thereby Establishing a Negative Feedback Loop. J. Biol. Chem., Vol. 280, Issue 52, 42785-42793.

Liman, J., Ganesan, S., Dohm, C.P., Krajewski, S., Reed, J.C., Bähr, M., Wouters, F.S. and Kermer, P. (2005) Interaction of BAG1 and Hsp70 Mediates Neuroprotectivity and Increases Chaperone Activity. Molecular and Cellular Biology, Vol. 25, Issue 9, 3715-3725.

Luo, W., Wang, Y., Hanck, T., Stricker, R. and Reiser, G. (2006) JAB1, A Novel Protease-Activated Receptor-2 (PAR-2) - Interacting Protein Is Involved in PAR-2-Induced Activation of AP-1. J. Biol. Chem. Papers in press. Published on January 12, 2006 as Manuscript M510784200.