We have proven and frequently published transfection solutions.
Powerful punch and versatility are now needed more than ever with the
hyper growth in gene manipulation technologies like Sleeping BeautyTM
and CRISPR-Cas9.
We have published examples of the use of our solutions for delivering siRNA, miRNA,
shRNA and plasmids both in vitro and in vivo. here are some of your options.
i-Fect ™ -A novel cationic lipid formulation specifically
designed for efficient delivery of 27mer DsiRNAs(dicer
substrate small Interfering RNAs)& 21mer siRNAs (small interfering RNAs) in vitro and in vivo.
p-Fect™ -Designed to delivery plasmids, DNA or
RNA to hard to transfect Cell Lines.
for primary neuronal cells.
This unique reagent provides ultra-high plasmid DNA delivery
efficiencies and low cytotoxicity compared to competitive reagents.
Here's a recent i-Fect Publication:
Liuming Jiang, Qun Wu , Tao Yang. Silencing of Id2 Alleviates
Chronic Neuropathic Pain Following Chronic Constriction Injury.
Journal of Molecular Neuroscience\pp 1-7.First online: 15 January 2016
Figure: Knockdown of Id2 attenuated mechanical allodynia and thermal
hyperalgesia in CCI rats. (a and b) PWT and PWL were measured 1 day before
CCI and 1, 3, 7, and 14 days after intrathecal administration of shRNA-Id2.
If you are looking for transfection solutions, do not hesitate to contact me @ direct phone: 612-801-1007 or pshuster@neuromics.com. Thank you, Pete Shuster, CEO and Owner, Neuromics